César Milstein

1927 – 2002 · Argentina · Medicine, Chemistry

Nobel Prize in Physiology or Medicine, 1984

Monoclonal antibodies — now a $200bn class of medicines.

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Continuity of ideas

Who shaped César Milstein, and who they shaped

Inherited from1

  • Macfarlane Burnet

    1899 – 1985 · Medicine, Biology

    Clonal selection theory is what makes a monoclonal antibody conceptually possible.

Passed the work to1

  • Katalin Karikó

    1955 · Medicine, Biology

    Monoclonal biologics established the manufacturing path modified-mRNA therapeutics followed.

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